All subjects enrolled will already have a baseline aortic diameter established at the time of initial AAA screening or diagnostic imaging. The investigators will recruit within a 3-year period a total of 200 subjects diagnosed with small AAA 3.0-5.4 cm diameter from the VA Northern California Health Care System. To streamline and better identify patients with small AAAs at risk for expansion, the investigators look to RhoA as a possible biomarker. However, follow up ultrasound protocols are difficult to follow, resulting in many patients with expanding AAA not being detected until too late. For patients with small AAA (3.0-5.4 cm) serial imaging studies is recommended along with risk factor modification. It is diagnosed typically by ultrasound when the aortic diameter is ≥ 3.0 cm and an aortic diameter ≥ 5.5 cm generally requires surgical repair to prevent rupture. Abdominal aortic aneurysm (AAA) is an asymptomatic problem until rupture occurs, causing excruciating pain and sudden death.
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